While the exact percentage of RA patients who experience sleep problems is hard to nail down, more than 80% of people with RA report fatigue as part of their symptoms. Why Sleep Matters Sleep problems can increase levels of stress hormones and aggravate flares, says Rochelle Rosian, MD, a Cleveland Clinic rheumatologist. What drug is similiar to plaquenil Folic acid and hydroxychloroquine dosing Plaquenil for inflammatory osteoarthritis A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including rash, itching/swelling especially of the face/tongue/throat, dizziness, trouble breathing. This is not a complete list of possible side effects. Maybe someone else will tell you differently, but I haven't known anyone else that found Plaquenil to make them tired. Pace and rest when you can and if you can exercise a little try to do that. My daughter couldn't exercise at all until recently. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. “When you sleep, you make all those brain chemicals that you need to feel better. And even if you’re not flaring, you may not manage your pain as well if you’re not sleeping. Does plaquenil make you sleepy Plaquenil, fatigue and dizziness, Does Plaquenil cause fatigue or fever? - Rheumatoid Arthritis Plaquenil and uctdRheumatoid arthritis guidelines hydroxychloroquine monotherapy Unless they are for a different reason like lungs and or heart. But I find that if I miss my plaquenil or NASID I feel miserable. Pain in my joints etc, the goal is to take a little of meds for them to be effective and make life worth living. Its not like they will make it go away. Can I take Plaquenil at night? - Sarcoidosis - Inspire. Foods to Avoid When Taking Plaquenil Oral. Plaquenil Side Effects Go Away? DailyStrength. Drowsiness is found among people who take Plaquenil, especially for people who are female, 50-59 old, have been taking the drug for 1 month, also take medication Enbrel, and have Pain. It is believed that 80% of lupus individuals will at one point or another deal with the tired-can’t-get-out-of-bed-can’t-move-out-of-spoons-feeling that seems to strike at the most inopportune times. And the sad part is, it is not something that a cup of joe or a 20 minute catnap will cure. It is something that seriously affects one’s relationships, job and overall quality of life. So, how do you identify the difference between lupus fatigue and normal everyday tiredness? Plaquenil can make you completely blind! *Legitimate looking vitamins I take to help remediate it I took Plaquenil for over 13 years and it caused me and 6 in every 1000 patients, new research shows to have toxic maculopathy it caused. *re even if you quit taking the drug, it can continue to damage the eye until blindness occurs.