It may have both an anti-spirochaete activity and an anti-inflammatory activity, similar to the treatment of rheumatoid arthritis. And caution is required if patients have certain heart conditions, diabetes, psoriasis etc. Hydroxychloroquine for frontal fibrosing alopecia Plaquenil and sulfasalazine Why does plaquenil work Do not take Plaquenil if you have ever had an allergic reaction to hydroxychloroquine, chloroquine, or related products or any of the ingredients listed under "Product Description". Binding of the drug to melanin in the RPE contributes to, or prolongs, its toxic effects. 2. Plaquenil toxicity is typically asymptomatic in early stages, but over time can lead to severe vision loss and retinal damage. Sue, I took mine breakfast & supper, to space them out. I bought a pill case for my handbag that's shaped like a pill capsule, as a graphic reminder to place by my plate. Had someone in a restaurant thinking it was a real pill once. Pretty funny, as it's huge. Hope the med kicks in for you well. Best wishes, from Vee For prolonged treatment of lupus or arthritis, adverse effects include the acute symptoms, plus altered eye pigmentation, acne, anaemia, bleaching of hair, blisters in mouth and eyes, blood disorders, convulsions, vision difficulties, diminished reflexes, emotional changes, excessive coloring of the skin, hearing loss, hives, itching, liver problems or liver failure, loss of hair, muscle paralysis, weakness or atrophy, nightmares, psoriasis, reading difficulties, tinnitus, skin inflammation and scaling, skin rash, vertigo, weight loss, and occasionally urinary incontinence. The most common adverse effects are a mild nausea and occasional stomach cramps with mild diarrhea. For short-term treatment of acute malaria, adverse effects can include abdominal cramps, diarrhea, heart problems, reduced appetite, headache, nausea and vomiting. Plaquenil pill shape Hydroxychloroquine Side Effects, Dosage, Uses, and More, How to Succeed in Plaquenil Screenings Chloroquine dose in vivax malaria Plaquenil is a drug used to treat Rheumatoid Arthritis and Systemic Lupus Erythematosis. It is a very good drug and gives many patients significant relief from their symptoms. Plaquenil related eye complications are not common. Plaquenil can produce pigment changes in the macula of the retina. Conditions Plaquenil-related Eye Problems Eugene Eye Care. Immune & Autoimmune - Lupus Plaquenil - when to take the 2.. Drug-induced nail disease DermNet NZ. Plaquenil by Aphena Pharma Solutions - Tennessee, Llc is a white double circle tablet about 12 mm in size, imprinted with product is a human prescription drug with active ingredients hydroxychloroquine sulfate. Pill Identifier. Having trouble identifying your pills? Enter the shape, color, or imprint of your prescription or OTC drug. Our pill identification tool will display pictures that you can compare to your pill. Hello all, I am currently new to this site and ran across the discussion about stopping Plaquenil. I have been taking Plaquenil for about 8-9 months and thought that it was not helping me because I still have a fair amount of joint pain, fatigue, muscle pain and so many other issues.