Chloroquine and malaria

Discussion in 'Canadian Drug' started by Yarik, 29-Feb-2020.

  1. Natalya Well-Known Member

    Chloroquine and malaria


    For decades, the drug was a front-line treatment and prophylactic for malaria. In a three-page paper published Tuesday in Cell Research, scientists at the Wuhan Institute of Virology’s State Key Laboratory of Virology write that both chloroquine and the antiviral remdesivir were, individually, “highly effective” at inhibiting replication of the novel coronavirus in cell culture.

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    The former may simulate an attack of cerebral malaria. When the diagnosis is in doubt the urine should be tested for porphobilinogen. Where self-medication is common and chloroquine is used without supervision to treat virtually any febrile condition, chloroquine abuse has been claimed to be a common cause of cardiac atrio-ventricular block. Chloroquine phosphate is in a class of drugs called antimalarials and amebicides. It is used to prevent and treat malaria. It is also used to treat amebiasis. This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information. You will need to talk about the benefits and risks of using chloroquine while you are pregnant. Preventing malaria Other measures are needed along with chloroquine including using screens, bed netting, insect repellent 10% to 35% DEET, and permethrin spray on clothing and nets. Avoid spraying most insect repellents on children.

    “It’s interesting in that it really lacks a lot of details but, nevertheless, if you look at the data as presented, at least in vitro, it seems like chloroquine can be used as an early-stage drug,” he said. Their drug screen evaluated five other drugs that were not effective. Though the paper is brief, John Lednicky, a professor at the University of Florida’s Emerging Pathogens Institute, found its results intriguing.

    Chloroquine and malaria

    Chloroquine Oral Route Proper Use - Mayo Clinic, Chloroquine MedlinePlus Drug Information

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  7. Chloroquine is the drug of choice for preventing and treating acute forms of malaria caused by P. vivax, P. malariae, P. ovale, as well as sensitive forms of P. falciparum. The mechanism of its action is not completely clear, although there are several hypotheses explaining its antimalarial activity.

    • Chloroquine - an overview ScienceDirect Topics.
    • Chloroquine Indications, Side Effects, Warnings -.
    • Chloroquine Oral Uses, Side Effects, Interactions..

    Areas with chloroquine-sensitive malaria include many Latin American countries where there is predominantly P. vivax malaria. Chloroquine-sensitive P. falciparum is present in the Caribbean and Central American countries west of the Panama Canal. For destinations where chloroquine-sensitive malaria is present, in addition to mosquito avoidance measures, the many effective prophylaxis options include chloroquine, atovaquone-proguanil, doxycycline, mefloquine, and tafenoquine. Chloroquine, a medication used to prevent and to treat malaria, has just been confirmed as one of the three anti-viral drug for Coronavirus. The search for the cure of Coronavirus has been on for some time now, and Chinese experts, based on the result of clinical trials, have confirmed that chloroquine phosphate, has a certain curative effect on the novel coronavirus disease COVID-19. Chloroquine is the generic form of the brand-name prescription medicine Aralen, which is used to prevent and treat malaria — a mosquito-borne disease caused by a parasite — and to treat amebiasis, an infection of the intestines caused by a parasite.

     
  8. sekir User

    The resource you are looking for (or one of its dependencies) could have been removed, had its name changed, or is temporarily unavailable. Plaquenil Side Effects on Your Eyes and Vision Hydroxychloroquine Side Effects, Dosage, Uses, and More What Is Hydroxychloroquine and How Does It Help Arthritis.
     
  9. bizmaker New Member

    Chloroquine Indications, Side Effects, Warnings - Do not start, stop, or change the dose of any drug without checking with your doctor. What are some things I need to know or do while I take Chloroquine? For all uses of chloroquine Tell all of your health care providers that you take chloroquine. This includes your doctors, nurses, pharmacists, and dentists.

    Chloroquine Dosage - Malaria Home Page