Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. What should a nurse monitor when taking hydroxychloroquine Chloroquine use salmonella resistance Recent studies suggest that hydroxychloroquine Plaquenil is safe for use during pregnancy.3 Nonsteroidal anti-inflammatory drugs NSAIDs such as ibuprofen and aspirin should be avoided during pregnancy unless prescribed by a doctor. Activation of the complement cascade might close the loop7 and provoke thrombosis and fetal loss 32-35occurs often in presence of a second hit. Traditional cardiovascular risk factors such as tobacco, inflammation, or oestrogens might have an important role at this point, in fact such risk factors are present in more than 50% of patients with antiphospholipid syndrome. OBJECTIVE The use of hydroxychloroquine HCQ in pregnancy remains controversial. The recent demonstration that HCQ passes across the placenta, with cord blood concentrations nearly identical to those found in maternal blood, emphasizes the need for careful evaluation of pregnancies in women receiving HCQ. Plaquenil is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. This medicine is not effective against all strains of malaria. Plaquenil for aps during pregnancy Too Little of a Good Thing Hydroxychloroquine in Pregnancy., Antiphospholipid Syndrome during pregnancy the state of the art Plaquenil hydroxychloroquine and lupusChloroquine resistance countries Plaquenil hydroxychloroquine has a good safety record in lupus pregnancy, and is usually continued if needed to control maternal lupus. Management and Monitoring Lupus pregnancy should be timed to coincide with a period of good disease control if at all possible. Lupus and Pregnancy Johns Hopkins Lupus Center. Safety of hydroxychloroquine in pregnant patients with.. Hydroxychloroquine MotherToBaby. In fact, many women experience improvement in their lupus symptoms during pregnancy. If you get pregnant after six months of remission, you’ll be less likely to experience a lupus flare than you. However, current management does not prevent all maternal, foetal and neonatal complications of APS. This observational, retrospective, single-centre cohort study aimed to assess pregnancy outcome in women with antiphospholipid antibodyaPL treated with hydroxychloroquine HCQ in addition to conventional treatment during pregnancy. Slow fetal growth can have several causes, most commonly hypertension, the presence of antiphospholipid antibodies, and/or lupus disease activity, especially lupus kidney disease. Impaired kidney function. The presence of lupus kidney disease also increases the chance of having complications during pregnancy.