While the mechanism is poorly understood, pregnant women have a reduced immune response and therefore less effectively clear malaria infections. In addition, malaria parasites sequester and replicate in the placenta. Plaquenil and liver transplant Does plaquenil suppress your immune system How long does plaquenil take to work for ra Chloroquine comes as a tablet, liquid, or injection. Your dose will depend on your medical condition, age, weight, and response to treatment. You can take this medicine with food if it causes an. Controlled studies evaluating the safety and efficacy of chloroquine in pregnant women. Usage of chloroquine during pregnancy should be avoided except in the suppression or treatment of malaria when in the judgment of the physician the benefit outweighs the potential risk to the fetus. PRECAUTIONS Hematological Effects/Laboratory Tests Chloroquine has not been formally assigned to a pregnancy category by the FDA. There are no controlled data in human pregnancies. Congenital anomalies were reported in the offspring of one woman being treated with chloroquine 250 to 500 mg daily during pregnancy for SLE; however, chloroquine has been used in the prophylaxis and treatment of malaria during pregnancy without evidence of fetal harm. Malaria infection during pregnancy can lead to miscarriage, premature delivery, low birth weight, congenital infection, and/or perinatal death. Pregnant women are three times more likely to develop severe disease than non-pregnant women acquiring infections from the same area. Effect of chloroquine injection on early pregnancy Chloroquine - Uses, Dosage, Side Effects, Composition., ASW-2F ARALEN® CHLOROQUINE PHOSPHATE, USP Interaction between hydroxychloroquine and methotrexateChloroquine effectiveness Find patient medical information for Chloroquine Injection on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Pregnancy Family & Pregnancy. Chloroquine Injection Uses, Side Effects, Interactions, Pictures.. Chloroquine Use During Pregnancy. Methotrexate and Pregnancy Is It Safe If You Have RA?. If you use other drugs or over the counter products at the same time, the effects of Chloroquine Injection may change. This may increase your risk for side-effects or cause your drug not to work properly. Chloroquine has a schizonticidal effect and kills the erythrocytic forms of malaria parasites at all stages of development, but does not affect the sporozoites inoculated by the mosquito or the malaria parasite in human liver cells. Chloroquine is a 9-aminoquinoline known since 1934. Apart from its well-known antimalarial effects, the drug has interesting biochemical properties that might be applied against some viral infections. Chloroquine exerts direct antiviral effects, inhibiting pH-dependent steps of the replication of several viruses including members of the flaviviruses, retroviruses, and coronaviruses. Its best.