It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Malaria is spread by mosquitoes, which transmit the parasites that cause the infection, usually in tropical and subtropical parts of the world. Plaquenil and lexapro Amoebic liver abscess treatment chloroquine Plaquenil and low dose naltrexone Plaquenil cost increase The effects of methotrexate and hydroxychloroquine combination therapy vs methotrexate monotherapy in early rheumatoid arthritis patients Lisa Schapink. Department of Rheumatology, Sint Maartenskliniek, the Netherlands. Department of Rheumatology, Radboudumc, Nijmegen, the Netherlands. The study is based on hydroxychloroquine sulfate and methotrexate sodium the active ingredients of Plaquenil and Methotrexate, respectively. Other drugs that have the same active ingredients e.g. generic drugs or brand names are also considered. Dosage of drugs is not considered in the study. I was diagnosed with RA in march and have been on increasing dose of methotrexate. Yesterday my rheumatologist started me on hydroxychloroquine as well. Is anyone else on this combination and have you had any problems with it as I know hydroxychloroquine can cause eye sight problems. Thanks For example, it may be combined with an antibiotic to treat chronic Q-fever, which humans usually catch from farm animals or raw milk. Plaquenil is used to treat other types of infections too. Is methotrexate the same as plaquenil Methotrexate or Plaquenil? DailyStrength, Plaquenil vs. Methotrexate side effect and effectiveness. What fillers are used in the manufacturing of hydroxychloroquinePlaquenil itchingPlaquenil side effects fluid retention Taking methotrexate with hydroxychloroquine has not been studied. It may increase your risk of side effects. Typical dosage is 400 mg once per week, taken on the same day each week, starting 2. Hydroxychloroquine Side Effects, Dosage, Uses, and More. Does anyone take methotrexate and hydroxychloroquine. - NRAS. Plaquenil hydroxychloroquine sulfate dose, indications, adverse.. By Connie Rifenburg June 3, 2015 at pm. Ang, I had hair loss pretty severe when I first started on Prednisone, Plaquenil, and Methotrexate. I guess it may depend on the dosage, and hopefully your hair loss will stop as mine did after a few months. OBJECTIVE To examine the bioavailability of methotrexate MTX in the presence of hydroxychloroquine HCQ, and vice versa, to determine a possible pharmacokinetic explanation for the observation that combination treatment of rheumatoid arthritis with MTX and HCQ has been shown, clinically, to be more potent than MTX used alone. Methotrexate vs plaquenil side effects long term and short term The only problem is the Plaquenil causes severe headaches that interfer with my daily activities also. But the Dr suggested I try Methotrexate instead.