Yesterday my rheumatologist started me on hydroxychloroquine as well. Is anyone else on this combination and have you had any problems with it as I know hydroxychloroquine can cause eye sight problems. Hydroxychloroquine sulphate weight gain Plaquenil skin side effects pictures If a particular preparation is ineffective after a 4-week trial or is not tolerated, then another NSAID can be initiated. No one NSAID has been demonstrated to be better than another for the treatment of rheumatoid arthritis nor have the COX-2 agents been shown to be superior to traditional NSAIDS in terms of effectiveness. Usual Time to Effect Hydroxychloroquine Plaquenil is used to treat malaria, lupus, and rheumatoid arthritis. Learn about side effects, warnings, dosage, and more. When monotherapy with a synthetic DMARD isn’t working well enough, consider a triple combination of hydroxychloroquine, methotrexate, and sulfasalazine. It works better than a two-drug combination methotrexate with either drug. Recently my eyes have felt sore and, after posting a question on this site, I am seeing my GP on Monday. Thanks Hi Catjones I have been taking this combination, started on both of them in January this year. Is plaquenil safer than methotrexate DMARDs Disease-Modifying Antirheumatic Drugs – CreakyJoints, Hydroxychloroquine Side Effects, Dosage, Uses, and More Plaquenil corneal toxicity Was the plaquenil controlling your RA symptoms? The trouble is you lose hair on Methotrexate too. But after losing heaps when I first went on it, I have stabalised now, I have thinner hair but it still looks fine and healthy. If plaq was working for your symptoms I'd go back on it. If you feel like the RA is escallating then go for mtx. Methotrexate vs Plaquenil? -. Choosing Medications for Rheumatoid Arthritis - NCBI Bookshelf. Plaquenil vs Methotrexate rheumatoid - reddit. Plaquenil is better than Sulfazalizine but the Arava is still more effective than the Plaq. Can't imagine Plaquenil by itself being very effective for moderate to severe. only good for mild cases. Keep in mind that Arava can really take a full three months to acheive full effectiveness. keep taking Plaq until then. January 2, 2013. One Chick is looking for your advice on medication My Rheumatologist recommended Methotrexate for my RA which I haven’t started taking yet because I was waiting until after the holidays in case I have side effectshowever she mentioned Plaquenil but she felt the Methotrexate is better for my RA. Jul 29, 2016 Not everyone will find relief with methotrexate, but it works better for more people than other DMARDs. If methotrexate treatment didn’t work for your RA the first time, there’s still hope. A.