It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Malaria is spread by mosquitoes, which transmit the parasites that cause the infection, usually in tropical and subtropical parts of the world. Does plaquenil take away the butterfly rash Plaquenil and teeth loss Hydroxychloroquine is an antimalarial medication that can cause hyperpigmentation of nails, mucosa, and skin 1–5. Retrospective studies cite the incidence of drug-related hyperpigmentation from hydroxychloroquine to be as high as 33% of individuals. Elder abuse is a cause of significant morbidity and mortality in older individuals 7–9. Bruises, or contusions, cause skin discoloration, swelling and tenderness. Sprained ankle. An ankle sprain is an injury the ligaments in the foot causing pain, tenderness, swelling, and bruising. Hematoma. A hematoma is a collection of blood in the tissue outside of a damaged blood vessel, usually after an injury. For example, in patients denying trauma, drug-induced blue-black macules have been confused with bruises and mistaken for evidence of elder abuse. 7 It is estimated that 10% to 20% of cases of. For example, it may be combined with an antibiotic to treat chronic Q-fever, which humans usually catch from farm animals or raw milk. Plaquenil is used to treat other types of infections too. Plaquenil induced bruising on shins Hydroxychloroquine Oral Route Side Effects - Mayo Clinic, Bruising or discoloration, Swelling and Swelling Common. Chloroquine is a prescriptionPlaquenil dosage guidelines SIDE EFFECTS. The following adverse reactions have been identified during post-approval use of PLAQUENIL or other 4-aminoqunoline compounds. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure. Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses. Painless, bruise-like hyperpigmentation on a woman with lupus.. Plaquenil Uses, Dosage & Side Effects -. Easy bruising sometimes indicates a serious underlying condition, such as a blood-clotting problem or a blood disease. See your doctor if you Have frequent, large bruises, especially if your bruises appear on your trunk, back or face, or seem to develop for no known reasons Immune thrombocytopenia ITP is a disorder that can lead to easy or excessive bruising and bleeding. The bleeding results from unusually low levels of platelets — the cells that help blood clot. Formerly known as idiopathic thrombocytopenic purpura, ITP can cause purple bruises, as well as tiny reddish-purple dots that look like a rash. Skin Hyperpigmentation with Hydroxychloroquine. Hydroxychloroquine Plaquenil is a common trade name is an anti-inflammatory oral medication that is commonly used to treat many autoimmune diseases. In the hair clinic, we use it for diseases such as lichen planopilaris, frontal fibrosing alopecia, pseudopelade and discoid lupus.