Rheumy says I can take them together or separately anytime I want. Hope that you won't suffer from the side effects. I have found that for me i can't take my Plaquenil before bed as it makes me anxious and makes it difficult to sleep. I’m thinking I’ll take them both together before bed. TIAI took them with breakfast but the first 6 weeks I suffered from extreme nausea as a side effect. I work overnights, so I take it before i go to work, then by the time I get home I am able to sleep ok. Hydroxychloroquine 200 mg for lupus Saliva drug test rx hydroxychloroquine false positive drug test If side effects do occur, they are usually minor and last only for a short period of time. Potential side effects of anti-malarial drugs include Skin rashes and pigment change. Atabrine, specifically, can cause yellow pigmentation of skin. Sometimes Plaquenil can also deposit in the tissues of the body and cause the skin to take on a greenish. I have just been reading that plaquenil can cause insomnia and nightmares which I suffer with. I take my plaquenil with my evening meal. When is the best time to take it? Would it be best in the morning? I also take in the morning thyroxine, omeprazole and co-codamol, would it interfere with any of those if I took it in the morning instead of. When I was on plaquenil twice a day my dr has reduced it now says I was taking too much for my weight, really. I would take one in the morning with breakfast and one at night after supper. It bothers my stomach so I find it is best to take it with food. One thing I have noticed, is mosquitoes tend not to target me, and I'm wondering if they taste the same yucky quinine flavor, and like us, aren't down with it. :)As for my routine, I took it at night, with or without food. I've had success taking it with a glass of milk, which is recommended on my perscription. I can get an upset stomach if I don't take them with milk or food right before. I always take it with food though, as it makes me nauseous otherwise. Almost 30 years, and it hasn't given me a speck of trouble, not even in the eyes. What is the best time to take plaquenil Can I take Plaquenil at night? - Sarcoidosis - Inspire, When best time of day to take plaquenil? - LUPUS UK Colchicine and hydroxychloroquineHydroxychloroquine cause rash This natural rhythm helps to explain why taking medicine to lower blood pressure may work best when done at night. "It better targets the morning rise in blood pressure,” Osborne said. Whereas, “if you take your blood pressure medicine in the morning, it may already be after the peak, and then the peak concentration of the drug is hitting a. When Is the Best Time to Take Your Blood Pressure Meds?. What time of day to take Plaquenil - Sjogren's World. Hydroxychloroquine Oral Route Precautions - Mayo Clinic. Hydroxychloroquine oral tablet is available as a brand-name drug and a generic drug. Brand name Plaquenil. Hydroxychloroquine comes only as a tablet you take by mouth. Ideal time for taking Plaquenil and side effects? Discussion in 'Medications' started by ilovedisney, Apr 12, 2011. Either contact your GP or rheumy and have them explain to you the best way to take your plaq.there may very well be a good reason it has been prescribed this way. Cally x cally, Apr 12, 2011 #2. In some cases, higher doses can be used. It is recommended one tablet twice daily if taking more than one tablet. It is recommended to be taken with food. Symptoms can start to improve in one to two months, but it may take up to six months before the full benefits of this medication are experienced.