Hydroxychloroquine is available as the brand-name drug Plaquenil. Generic drugs usually cost less than the brand-name version. Hydroxychloroquine may be used as part of a combination therapy. Plaquenil cost for generic Hydroxychloroquine mechanism of action for lupus Does plaquenil cause headaches Hydroxychloroquine is commonly used alongside other disease-modifying drugs including methotrexate – especially for rheumatoid arthritis. However, some drugs can interact with hydroxychloroquine. Indigestion remedies for example, antacids including some over-the-counter preparations can stop hydroxychloroquine being absorbed. Half-life T ½ In a bioavailability study of 5 healthy participants receiving 1 oral and 1 intravenous IV dose of hydroxychloroquine sulfate 200 mg 155 mg base administered on separate occasions, the mean terminal elimination half-life of hydroxychloroquine, as calculated from blood data, was more than 40 days for both the oral and IV. Hydroxychloroquine is in a class of drugs called antimalarials. It is used to prevent and treat acute attacks of malaria. It is also used to treat discoid or systemic lupus erythematosus and rheumatoid arthritis in patients whose symptoms have not improved with other treatments. Hydroxychloroquine is used to treat lupus erythematosus and rheumatoid arthritis. It isn’t fully understood how this drug works to treat lupus erythematosus or rheumatoid arthritis. That means you may need to take it with other drugs. It treats malaria by killing the parasites that cause the disease. Hydroxychloroquine shelf life Hydroxychloroquine Sulfate Drug Information, Professional, Hydroxychloroquine Information for Providers AIDSinfo Weight gain while using plaquenilHydroxychloroquine organ damage Mar 10, 2020 In one study, mean peak plasma hydroxychloroquine concentrations following a single dose of 400mg in healthy subjects ranged from 53-208 ng/ml with a mean of 105ng/ml. The mean time to peak plasma concentration was 1.83 hours. The mean plasma elimination half-life varied, depending on the post administration period. Plaquenil-Hydroxychloroquine sulfate 200mg Film-coated.. Hydroxychloroquine MedlinePlus Drug Information. Hydroxychloroquine Indications, Side Effects, Warnings.. Find patient medical information for Hydroxychloroquine Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Hydroxychloroquine HCQ, sold under the brand name Plaquenil among others, is a medication used for the prevention and treatment of certain types of malaria. Specifically it is used for chloroquine-sensitive malaria. Other uses include treatment of rheumatoid arthritis, lupus, and porphyria cutanea tarda. It is taken by mouth. It is also being used as an experimental treatment for SARS-CoV-2. To prevent malaria, take chloroquine once weekly on the same day each week, or as directed by your doctor. Start this medication usually 1 to 2 weeks before you enter the malarious area, continue to take it weekly while in the area, and weekly for 4 to 8 weeks after leaving the area, or as directed by your doctor.