Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Plaquenil lower platelets Is plaquenil an nsaid drug Hydroxychloroquine Plaquenil is a drug that is classified as an anti-malarial drug. Plaquenil is prescribed for the treatment or prevention of malaria. It is also prescribed for the treatment of rheumatoid arthritis, lupus, and the side effects of lupus such as hair loss, joint pain, and more. Low platelet count is also a side effect of disease-modifying drugs, including methotrexate and biologics. Aspirin or other NSAIDs can affect blood clotting, and corticosteroid use causes the capillaries to become fragile and more likely to break and cause a bruise if you bump into something. An occasional bruise is nothing to be concerned about. Plaquenil and Thrombocytopenia - from FDA reports Summary Thrombocytopenia is found among people who take Plaquenil, especially for people who are female, 60+ old, have been taking the drug for 2 - 5 years, also take medication Enbrel, and have High blood pressure. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Can plaquenil cause low platelets Relapsed Hydroxychloroquine Induced Thrombocytopenia in., Symptoms Not to Ignore - Living With Arthritis Hydroxychloroquine interactions in dental treatmentCan i get the best price for hydroxychloroquine sulfate Ab- normally high MPV, which occurs when the body constantly creates new platelets, has been linked to various cardiovascular diseases like coronary artery disease, hypertension and stroke 2. This is because larger platelets have a more difficult time traveling through the blood stream and can more easily get stuck and block your arteries. Vitamin D deficiency may be associated with increased.. Will you have Thrombocytopenia with Plaquenil - eHealthMe. Kidney Biopsy/Low Platelets" Lupus Community - Support Group. Plaquenil - Effects on Blood Tests especially platelet count This is my first post on the board. I was dx with Lupus in May, after being "treated" for idiopathic thrombocytopenia purpura for three and a half years. Some of the dosage forms listed on this page may not apply to the brand name Plaquenil. For the Consumer. Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine the active ingredient contained in Plaquenil may cause some unwanted effects. Although not all of these side effects may occur, if they do occur. Low platelets may result from a number of factors, but often this condition occurs in cancer patients from radiation and chemotherapy treatments. Most commonly known as thrombocytopenia, low platelet levels compromise your body's ability to effectively clot your blood 2. Other possible causes include medications or severe injury resulting in.