Chloroquine is now uncommonly used in favor of its derivative hydroxychloroquine. In the United States, hydroxychloroquine is most often used for its anti-inflammatory effects in rheumatology and dermatology. Fibro and plaquenil Is plaquenil a steroid an immunosuppressant K63 ub after chloroquine Leflunomide methotrexate and hydroxychloroquine Diagnosis Hydroxychloroquine-induced retinal toxicity Discussion. Chloroquine CQ and hydroxychloroquine Plaquenil HCQ have been used for many years, initially for the treatment of malaria but now more commonly for the treatment of inflammatory diseases such as rheumatoid arthritis and lupus 1. It is now considered for new disease applications in diabetes, heart disease and adjunct cancer therapies 2. Hydroxychloroquine retinopathy. It is known that some people who take hydroxychloroquine for more than five years and/or in high doses are at increased risk of damage to their retina, the light sensitive layer of cells at the back of the eye. This is known as retinal toxicity or retinopathy. Hydroxychloroquine HCQ, brand name Plaquenil is commonly used for the long-term 2 management of a variety of chronic rheumatic diseases including systemic lupus erythematosus 3 and rheumatoid arthritis. While early toxicity may be asymtomatic, patients with more advanced stage of toxicity may complain of color vision changes or paracentral scotomas. Its toxic effects on the retina are seen in the macula. Plaquenil maculopathy monitoring Hydroxychloroquine toxicity - EyeWiki, Hydroxychloroquine screening Deae dextran chloroquine methodChloroquine dose in child May 16, 2011 Hydroxychloroquine Plaquenil; HCQ has been an important and effective drug for the treatment of lupus erythematosus and related autoimmune and inflammatory diseases for half a century, although its potential to cause retinal damage continues to raise concern among rheumatologists and ophthalmologists. Hydroxychloroquine Retinopathy Still Alive and Well - The.. AMERICAN COLLEGE OF RHEUMATOLOGY. Plaquenil-Induced Toxic Maculopathy - Decision-Maker PLUS. Ensure baseline monitoring of full blood count, biochemical profile ophthalmological examination and muscle function. Discuss how the patient / carer can be aware of possible signs hydroxychloroquine toxicity or intolerance Provide written instruction to the GP for initiation and escalation of hydroxychloroquine. The Royal College of Ophthalmologists has recently developed new guidelines for the monitoring of hydroxychloroquine retinopathy. These were developed in collaboration with colleagues from. Hydroxychloroquine Plaquenil® is a 4-amino-quinoline antimalarial medication that is widely used to treat systemic lupus erythematosus SLE, rheumatoid arthritis, and related inflammatory and dermatological conditions. It is a hydroxylated version of chloroquine, with a similar mechanism of action.