And is one of several anti-malarial medications recommended by the United States Centers for Disease Control and Prevention for this purpose. It is also recommended by the Infectious Disease Society of America for malaria prophylaxis as a first or second-line agent, depending on resistance patterns in the malaria found in the geographic region visited. How long chloroquine tablets is good afternoon Potential adverse effect with hydroxychloroquine Drug Mefloquine can prolong cardiac conduction in patients taking beta blockers, calcium channel blockers, and possibly digoxin. Quinine may decrease plasma mefloquine concentrations. Mefloquine may decrease valproic acid serum concentrations by increasing its hepatic metabolism. Administration with chloroquine may increase Chloramphenicol is an inhibitor of this enzyme and may decrease the clearance of mefloquine and increase mefloquine systemic exposure. Chloroquine Major Due to the potential for QT prolongation and torsade de pointes TdP, caution is advised when administering chloroquine with mefloquine. In addition, concurrent use may result in seizures. Dose expressed as mefloquine hydrochloride i.e. as the salt. Administration advice-Do not administer on an empty stomach; administer with at least 8 ounces 240 mL of water.-Tablets may be crushed and suspended in a small amount of water, milk, or other beverage for patients unable to swallow them whole. Storage requirements Mefloquine does not eliminate parasites in the liver phase of the disease, and people with P. Mefloquine is used as a treatment for chloroquine-sensitive or resistant Plasmodium falciparum malaria, and is deemed a reasonable alternative for uncomplicated chloroquine-resistant Plasmodium vivax malaria. Mefloquine hydrochloride chloroquine Mefloquine Professional Patient Advice -, Mefloquine Hydrochloride mefloquine hydrochloride dose. Drug interactions hydroxychloroquinePlaquenil effects menstrual cycleHydroxychloroquine substitutionsChloroquine administrationHydroxychloroquine gingival hyperplasia Provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Data sources include IBM Watson Micromedex updated, Cerner Multum™ updated, Wolters Kluwer™ updated. Mefloquine Side Effects Common, Severe, Long Term -. Mefloquine Dosage Guide with Precautions -. LARIAM brand of mefloquine hydrochloride TABLETS R. How to use Mefloquine HCL. Read the Medication Guide provided by your pharmacist before you start taking mefloquine and each time you get a refill. If you have any questions, ask your doctor or. Mefloquine Hydrochloride Oral tablet drug summary. Find medication information including related drug classes, side effects, patient statistics and answers to frequently asked questions. Visit for more details. WebMD provides information about interactions between Mefloquine Oral and mefloquine-chloroquine-quinidine-quinine. mefloquine hydrochloride US prescribing information. Karbwang J, Back.