Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. Hydroxychloroquine tab Chloroquine site drugs.com Difficulty sleeping, & may experience nightmares • ringing in the ears and/or altered hearing • muscle weakness • damage to the back of the eye retina. Symptoms include difficulty reading or seeing parts of words, or objects may be missing or blurred vision. When plaquenil is taken in Been off of plaquenil for about 5 months and I can tell difference of my sleep. I sleep more hours during those periods I stop taking plaquenil. Now, that I am back taking plaquenil I could hardly sleep. I think I just sleep 2 hours or less or a little bit more than 2 hours each night. Does anyone. Provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Plaquenil is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. This medicine is not effective against all strains of malaria. Plaquenil difficulty sleeping Plaquenil Uses, Dosage & Side Effects -, Insomnia because of plaquenil DailyStrength Plaquenil for connective tissue diseaseChloroquine phoenix cellsChloroquine itch mouse behaviorChloroquine therapeutic class If rheumatoid arthritis has you tossing and turning at night, you’re not alone. While the exact percentage of RA patients who experience sleep problems is hard to nail down, more than 80% of people with RA report fatigue as part of their symptoms. Rheumatoid Arthritis and Sleep Arthritis Foundation. Plaquenil Side Effects Common, Severe, Long Term -. Anxiety and Plaquenil Has anyone experienced mood.. Getting Better Sleep A good night’s sleep will improve your pain and ability to manage it. You can get more restful sleep. Review your medications with your doctor or pharmacist to see if they affect sleep. Get checked for physical problems like sleep apnea that may be contributing to sleep problems. Less than a month after starting Plaquenil I started having problems with insomnia and some anxiety. I'm still struggling to sleep well without waking up and lying awake for hours. I'm also a little backed up and starting some Miralax and dulcolax for that, hoping it might help with the sleep as well. Good luck. What is Plaquenil? Plaquenil hydroxychloroquine is a medication most known for its original purpose of treating or preventing malaria, a disease caused by parasites that enter the body through the bite of a mosquito.