It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Malaria is spread by mosquitoes, which transmit the parasites that cause the infection, usually in tropical and subtropical parts of the world. Chloroquine base lethal dose Plaquenil and lupus rash Hydroxychloroquine Plaquenil is a drug that is classified as an anti-malarial drug. Plaquenil is prescribed for the treatment or prevention of malaria. It is also prescribed for the treatment of rheumatoid arthritis, lupus, and the side effects of lupus such as hair loss, joint pain, and more. If you are taking Plaquenil to treat an inflammatory condition or malaria, you should be aware of the side effects that may occur to your eyes and vision. Plaquenil hydroxychloroquine is in a class of drugs called disease-modifying anti-rheumatic drugs, which are used to decrease inflammation, pain and joint damage. Along with its needed effects, hydroxychloroquine the active ingredient contained in Plaquenil may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine For example, it may be combined with an antibiotic to treat chronic Q-fever, which humans usually catch from farm animals or raw milk. Plaquenil is used to treat other types of infections too. Plaquenil ophthalmic side effects Hydroxychloroquine Side Effects, Dosage, Uses, and More, Plaquenil Side Effects on Your Eyes and Vision Plaquenil retinopathy info for patient rheumatol Potential Plaquenil side effects include nightmares, weight loss, and diarrhea. This eMedTV resource provides a list of other possible side effects of Plaquenil, including serious ones that require medical attention such as hearing loss or seizures. Plaquenil Side Effects - Antibiotics Home Page. Plaquenil Side Effects Common, Severe, Long Term -. Plaquenil Side Effects Common, Severe, Long. Download PDF. Drug-induced ocular side effects are back in the spotlight, thanks to the Academy’s revision of its recommendations on screening for retinal toxicity from chloroquine and its analogue hydroxychloroquine Plaquenil. 1 There are hundreds of drugs with potential retinal toxicity—so many that the National Registry of Drug-Induced Ocular Side Effects doesn’t stratify them by. And of greater importance, Plaquenil has less systemic side effects than other drugs used for lupus, so there is a real advantage in using it as long as one can. Modi YS, et al. Ophthalmic. Plaquenil can cause serious side effects when used in high doses for chronic diseases such as RA over the long term. The New Zealand Dermatological Society recommends that to decrease the risk of retina damage, no more than 200mg of Plaquenil should be taken a day, and a dose of 400mg per day should be taken no longer than a few weeks.