It does not work against certain types of malaria (chloroquine-resistant). The United States Center for Disease Control provides updated guidelines and travel recommendations for the prevention and treatment of malaria in different parts of the world. Generic plaquenil shortage What do plaquenil pills look like Chloroquine dosing retina recommendation Plaquenil for scleroderma My doctor put me on prednisone at the same time with plaquenil and it was within a month I started noticing it helping. He said it would help in the meantime it takes the plaquenil to get absorbed in my body. Hopefully I'll be done with the prednisone in a couple weeks as it makes me bloated. That was my rheumatologist and he has been the best. Things like vitamins and exercise might assist with decreasing the fatigue level. I have been on 2 Dmards and a biologic for the longest time. I also take Tramadol for pain and now Indomethicin has been added to the mix to help with stiffness. I take Nsaids for pain to get me through a work day when I am having a tough time. I have just been reading that plaquenil can cause insomnia and nightmares which I suffer with. I take my plaquenil with my evening meal. When is the best time to take it? Would it be best in the morning? I also take in the morning thyroxine, omeprazole and co-codamol, would it interfere with any of those if I took it in the morning instead of. This medication is also used, usually with other medications, to treat certain auto-immune diseases (lupus, rheumatoid arthritis) when other medications have not worked or cannot be used. Discuss the most recent information with your doctor before traveling to areas where malaria occurs. Plaquenil time to work Lupus Medicines Hydroxychloroquine - Brigham and Women's., Plaquenil for fatigue and pain DailyStrength Will i lose all of my hair when taking plaquenilCalcium chloroquine How long does it take for plaquenil to work? I just started about 6 weeks ago, the rheum said it can take up to a year. Let me know how you are doing on it! Plaquenil - does it take long time to work? - Lupus - Inspire. When best time of day to take plaquenil? - LUPUS UK. Hydroxychloroquine Plaquenil. Hydroxychloroquine doesn’t work immediately. It may be 12 weeks or longer before you notice any benefit. Because it's a long-term treatment it's important to keep taking hydroxychloroquine unless you have severe side-effects even if it doesn't seem to be working at first; even when your symptoms improve to help keep the disease under control. If you are taking it on a daily schedule, take it at the same time each day. Take this medication exactly as prescribed. Do not stop taking it without talking with your doctor, especially if you. Plaquenil is a slow-acting drug, meaning that it can take up to 6 months to experience the full benefits of this medication, but it is possible for symptoms to improve in as few as 1 or 2 months. Plaquenil and other antimalarials are the key to controlling lupus long-term, and some lupus patients may be on Plaquenil for the rest of their lives.