Alternatively, we suggest using this opportunity to take a little break from work and read some of the interesting articles below. Download PDF Many systemic medications may cause retinal toxicity. Plaquenil ehlers danlos Can plaquenil cause alopecia Scleroderma plaquenil Chloroquine retinal cell Background. The American Academy of Ophthalmology recommendations for screening of chloroquine CQ and hydroxychloroquine HCQ retinopathy were published in 2002, but improved screening tools and new knowledge about the prevalence of toxicity have appeared in the ensuing years. Chloroquine retinopathy, is a form of toxic retinopathy damage of the retina caused by the drugs chloroquine or hydroxychloroquine, which are sometimes used in the treatment of autoimmune disorders such as rheumatoid arthritis and systemic lupus erythematosus. This eye toxicity limits long-term use of the drugs. The American Academy of Ophthalmology released revised recommendations on screening for chloroquine and hydroxychloroquine retinopathy in 2016. All patients must undergo a baseline dilated fundus. It is used to treat many diseases including malaria, rheumatoid arthritis and systemic lupus erythematosus. One such commonly used medication for dermatologic and rheumatologic inflammatory conditions is hydroxychloroquine (Plaquenil), a chloroquine derivative. Chloroquine maculopathy screening Drug induced maculopathy - EyeWiki, Chloroquine retinopathy - Wikipedia Malaria prophylaxis chloroquine resistant areasPlaquenil treatment for vasculitisLupus medication plaquenil side effectsChloroquine nhibts clathrin mediated endocytosisSide effects plaquenil forums The subjective component to HCQ retinopathy screening is an automated visual field testing the central 10° of vision. The earliest signs of HCQ retinopathy on a central visual field may present as a cluster of paracentral points with decreased sensitivity. These points may be only mildly depressed. Hydroxychloroquine retinopathy A review of imaging. Chloroquine and Hydroxychloroquine Toxicity Guidelines.. Hydroxychloroquine Maculopathy An Update on Screening and.. Some patients, toxicity may first present as pericentral retinopathy and thus requires screening outside the macula. We assume chloroquine retinopathy follows a similar course as hydroxychloroquine retinopathy and so these guidelines also apply to patients taking chloroquine therapy. The recommendations on eye screening for hydroxychloroquine or chloroquine retinopathy have been revised by the American Academy of Ophthalmology. 22 It is strongly recommended that all patients beginning hydroxychloroquine or chloroquine therapy have a baseline examination within the first year of starting the drug to document any complicating. Hydroxychloroquine and Retinal Screening. Hydroxychloroquine is used routinely in the early arthritis pathway for new onset rheumatoid arthritis alongside methotrexate and is also used in connective tissue diseases. It is normally initiated by rheumatologists or dermatologists with prescribing being shared with GPs after a period of stabilisation.