Hydroxychloroquine is available as the brand-name drug Plaquenil. Generic drugs usually cost less than the brand-name version. Hydroxychloroquine may be used as part of a combination therapy. Hydroxychloroquine patient Quinine plaquenil Does methotrexate work without plaquenil Plaquenil and glutamate Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Hydroxychloroquine belongs to the family of medicines called “antimalarials” AMs, which are also classified as disease-modifying anti-rheumatic drugs, or DMARDs. These drugs were initially used to prevent and to treat malaria but are no longer used for those purposes; more effective drugs have since been developed. From InfantRisk Hydroxychloroquine HCQ is effective in the treatment of malaria but is also used in immune syndromes such as rheumatoid arthritis and systemic lupus erythematosus SLE. Due to its huge volume of distribution, milk levels are generally quite low, and therefore this drug maybe considered compatible with breastfeeding. Hydroxychloroquine is used to treat lupus erythematosus and rheumatoid arthritis. It isn’t fully understood how this drug works to treat lupus erythematosus or rheumatoid arthritis. That means you may need to take it with other drugs. It treats malaria by killing the parasites that cause the disease. Hydroxychloroquine and breastfeeding Drugs for Lupus While Breastfeeding Breastfeeding Medicine, Drug spotlight on hydroxychloroquine Lupus Foundation of. Cyclosporine and plaquenilDiluting chloroquine for in vivo treatments However, children are more sensitive to the effects of this medicine than adults. Safety and efficacy of hydroxychloroquine to treat lupus and arthritis have not been established in children. Hydroxychloroquine Oral Route Before Using - Mayo Clinic. Hydroxychloroquine and Breastfeeding - Help? breastfeeding. Hydroxychloroquine Side Effects, Dosage, Uses, and More. Plaquenil hydroxychloroquine is an antimalarial medication used to treat or prevent malaria, a disease caused by parasites, which enter the body through the bite of a mosquito. Plaquenil is also used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Hydroxychloroquine Plaquenil® is a 4-amino-quinoline antimalarial medication that is widely used to treat systemic lupus erythematosus SLE, rheumatoid arthritis, and related inflammatory and dermatological conditions. It is a hydroxylated version of chloroquine, with a similar mechanism of action. Hydroxychloroquine is usually considered a pregnancy Category C medication. This means that it may not be safe for use during pregnancy, although the full risks are not known. Talk to your healthcare provider about the risks and benefits of using hydroxychloroquine during pregnancy see Plaquenil and Pregnancy for more information.