One such commonly used medication for dermatologic and rheumatologic inflammatory conditions is hydroxychloroquine (Plaquenil), a chloroquine derivative. It is used to treat many diseases including malaria, rheumatoid arthritis and systemic lupus erythematosus. Synthesis of chloroquine phosphate slideshare What eye exam is needed for plaquenil Primaquine chloroquine interaction Hydroxychloroquine comes in 200 mg tablets and is taken orally. The dose provided will be based upon a calculation of 6.5 mg/kg subject’s weight, which is the dose range commonly used to treat rheumatoid arthritis and lupus. Dosages will be rounded to the nearest 100 mg. Taken orally once a day. Administration during or after meals. Prescribing providers may not routinely calculate the optimal dose of hydroxychloroquine due to a number of factors, including 1 toxicity is a cumulative effect and takes years to develop; 2 the calculations are cumbersome and time during a clinical encounter is short; 3 lack of familiarity with recommended dosing guidelines; and 4. The Hydroxychloroquine Dosing Calculator calculates appropriate daily dose of hydroxychloroquine. It is imperative that patients and physicians are aware of and watch for this drug’s ocular side effects. Retinal toxicity from hydroxychloroquine is rare, but even if the medication is discontinued, vision loss may be irreversible and may continue to progress. Hydroxychloroquine dosage calculator Despite Plaquenil dosing recommendations, retinal toxicity., Dosechecker Solving the Hydroxychloroquine Dosing Dilemma. Hydroxychloroquine and tattoosEffects of plaquenil rx on osteoarthritisPlaquenil and intestinal problems Medscape - Indication-specific dosing for Plaquenil hydroxychloroquine sulfate, frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & lactation schedules, and cost information. Plaquenil hydroxychloroquine sulfate dosing, indications.. Hydroxychloroquine Plaquenil Dosing Calculator - MDCalc. Ideal Body Weight for Calculating Hydroxychloroquine Dosage.. The recommended Plaquenil dosage for malaria prevention is 400 mg once weekly, starting two weeks before the anticipated exposure. The usual starting dosage for treating lupus is 400 mg once or twice a day, and the recommended starting dose for the treatment of rheumatoid arthritis is 400 to 600 mg daily. Ideal body weight Plaquenil dosing calculations are reprinted with permission from The Lupus Encyclopedia A Comprehensive Guide for Patients and Families, by Donald E. Thomas, published by Johns Hopkins University Press. A new study investigating plaquenil hydroxychloroquine or HCQ toxicity and dosing, The Risk of Toxic Retinopathy in Patients on Long-term Hydroxychloroquine Therapy 1, was published last year. This has prompted me to reevaluate and rewrite EyeDock’s plaquenil risk calculator.