I did stop it for 2 weeks early in the treatment due to having to take a coupld other drugs that seemed to give me side effects. I just quit the plaquenil to give my liver a rest at that time. Plaquenil isn a antiparasitic drug with anti-inflammatory affect. Symptoms of eye damage from plaquenil Plaquenil heart racing I panicked and quit because my hair was really thinning and breaking off. I have done more online research and have come to the conclusion that LUPUS alone makes your hair thin and break. I am going back on the Plaquenil, I think, on my next appt. I believe it worked well for me. I took 100mg twice a day. I agree with the idea of tapering if. If you've successfully tapered off opioid pain medication in the past, taking opioids for a brief time — with guidance from your doctor — may be appropriate. Discuss all your medication and pain management options, including pros and cons, with your doctor. Let your doctor know whether you had any trouble tapering off opioids in the past. Nov 14, 2006 I have been taking Plaquenil 400 mg per day for about 2 years now due to lupus flare. When i first started it, I was also started on prednisone to get my inflammation under control. Actually I started on 200 mg per day and about 2 months before tapering off pred, he upped me to 400 mg per day of plaquenil to give it plenty of time to kick in. Over the years on this site we have had quite a few people post that they didn't think that the plaquenil was working so they would stop taking it. I have done a lot of research on this drug and haven't run into anybody who has complained of the withdrawal effect. How to taper off of plaquenil Can you quit plaquenil cold turkey, or have to wean, Tapering off opioids When and how - Mayo Clinic What is plaquenil toxicityPlaquenil and codeinePlaquenil and lexapro Hi everybody! I recently went to the doc and he recommended that I try cutting my Plaquenil in half from 400mg to 200mg/day. I have been on it since March, 2002. It's been about a week and I have noticed a few slight changes, mainly a little stiffness in my fingers and feeling a little fatigued. Healthboards - Immune & Autoimmune - Lupus tapering Plaquenil. Plaquenil -. Stopping plaquenil. DailyStrength. Welcome to Sclero Forums! It is delightful to have you join us. I think your experience with going off plaquenil is very helpful for the rest of us to know about. You can let go of being angry at yourself, if you want. You didn't know for sure, ahead of time, that your health would worsen when you went off of plaquenil, did you? Proper Use. Drug information provided by IBM Micromedex Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. Plaquenil is prescribed as a disease-modifier, in other words, to decrease pain, decrease swelling, and prevent joint damage and disability. It is not known how Plaquenil works but researchers believe that Plaquenil interferes with communication between cells within the immune system. Ultimately, it is thought to block proinflammatory.