Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. Can hydroxychloroquine get you high How to reduce stomach discomfort with plaquenil Withdrawal from plaquenil The most common side effects are nausea and diarrhea, which often improve with time. Less common side effects include rash, changes in skin pigment such as darkening or dark spots, hair changes, and muscle weakness. Rarely, hydroxychloroquine can lead to anemia in some individuals. Side effect rates for Plaquenil hydroxychloroquine Manufacturers don’t say how common these side effects are when taking Plaquenil for null. Nausea. Vomiting. Diarrhea. Stomach cramps. Rash serious skin conditions in rare cases Headache. Dizziness. Changes in mood. Vision changes. Sensitivity to. Check with your doctor immediately if any of the following side effects occur Incidence not known. Blistering, peeling, loosening of the skin blurred vision or other vision changes chest discomfort, pain, or tightness cough or hoarseness dark urine decreased urination defective color vision diarrhea difficulty breathing Plaquenil is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. This medicine is not effective against all strains of malaria. Hydroxy chloroquine rheumatoid arthritis side effects Hydroxychloroquine - Wikipedia, Plaquenil hydroxychloroquine Basics, Side Effects & Reviews - Plaquenil ophthalmology retina specialist 2018 Nov 09, 2018 Hydroxychloroquine is also used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Hydroxychloroquine may also be used for purposes not listed in this. Hydroxychloroquine - Side Effects, Dosage, Interactions.. Hydroxychloroquine Oral Route Side Effects - Mayo Clinic. What are the side effects of using hydroxychloroquine.. Many people using this medication do not have serious side your doctor immediately if any of these unlikely but serious side effects occur arm/leg/ back pain, fast heartbeat, hair loss /color change, mental/mood changes e.g. anxiety, depression, hallucinations, ringing in the ears / hearing loss. A more chronic form of interstitial lung disease and fibrosis is also seen in patients with rheumatoid arthritis. This may be increased with methotrexate. Myelosuppression lowering of blood counts is also rare at the low doses of methotrexate utilized for rheumatoid arthritis. Patients at particular risk include those with renal insufficiency from other causes or use of trimethoprim Bactrim®, Septra® which increases levels of methotrexate. Long-Term Side Effects of Plaquenil for Rheumatoid Arthritis. Plaquenil is the brand name of hydroxychloroquine, a drug used to prevent or treat malaria. Plaquenil is also used for long-term treatment of autoimmune diseases such as rheumatoid arthritis RA and systemic lupus erythmatosis.