In people with sarcoidosis, abnormal masses or nodules (called granulomas) consisting of inflamed tissues form in certain organs of the body. These granulomas may alter the normal structure and possibly the function of the affected organ(s). Hydroxychloroquine in pregnancy Plaquenil dosage lyme Plaquenil exfoliative dermatitis Drug aralen Chloroquine CQ can be an effective treatment for lung sarcoidosis with few side effects, but has not been accepted as standard therapy. We investigated the benefits of prolonged CQ therapy in 23 symptomatic patients with biopsy-proven pulmonary sarcoidosis duration, ⩾ 2 yr. Conclusion This study shows hydroxychloroquine is safe and effective in the treatment of pulmonary sarcoidosis, particularly multisystem disease. We conclude, therefore, that hydroxychloroquine should be considered in the treatment and maintenance of patients with chronic pulmonary sarcoidosis. The severe form of sarcoidosis slowly worsens over a period of years, and can cause permanent organ damage. Treatment can help, but the disease may still leave scar tissue in the lungs, skin, eyes or other organs. Between 20 and 30 percent of people with pulmonary sarcoidosis end up with permanent lung damage. Most patients initially complain of a persistent dry cough, fatigue, and shortness of breath. The symptoms of sarcoidosis can vary greatly, depending on which organs are involved. Plaquenil pulmonary sarcoidosis Sarcoidosis Treatment the lung association, Experience of hydroxychloroquine in the treatment of. Plaquenil and osteoarthritis Pulmonary sarcoidosis is the most common manifestation of sarcoidosis as the lungs and/or hilar and mediastinal nodes are involved in about 90 percent of patients. Dyspnea, dry cough, and chest pain are the most common pulmonary symptoms. Sarcoidosis - Pulmonology Advisor. SARCOIDOSIS -. What medications treat sarcoidosis?. Hydroxychloroquine and chloroquine These oral antimalarial drugs have been used to treat sarcoidosis of the skin, lungs, and nervous system. They are used to treat the hypercalcemia seen with sarcoidosis. Patients on these drugs need occasional monitoring of their eyes by an ophthalmologist. Pulmonary sarcoidosis is an inflammatory condition where abnormal tissue forms in the lungs. Often the lymph nodes within the chest cavity are also affected. This abnormal tissue is known as a granuloma and is the type of tissue that arises when the body tries to wall off an infection. Sarcoidosis can affect almost any organ in the body. But the most common target is the lung. Although doctors do not know the exact cause of sarcoidosis, there is strong evidence that the illness involves an abnormal immune reaction.