Hydroxychloroquine is available as the brand-name drug Plaquenil. Generic drugs usually cost less than the brand-name version. Hydroxychloroquine may be used as part of a combination therapy. Chloroquine and primaquine What autoimmune diseases does does plaquenil treat My rheumy has just prescribed Plaquenil for my SS. Reading the warnings, I see that there is concern about effects on the eyes retinas. I am very concerned about this and am wondering if anyone out there has been put on an alternative drug to treat their SS. I have several issues with my. May 20, 2008 Because the action of Plaq isn't really understood in SjS, and it's a unique classification of drug in treating AIs, there really isn't a substitute for it, but there are other classes of drugs, also called DMARDS disease modifying anti-rheumatic drugs that are also used. Side Effects Nausea, stomach cramps, loss of appetite, diarrhea, dizziness, or headache may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly. Remember. Hydroxychloroquine is used to treat lupus erythematosus and rheumatoid arthritis. It isn’t fully understood how this drug works to treat lupus erythematosus or rheumatoid arthritis. That means you may need to take it with other drugs. It treats malaria by killing the parasites that cause the disease. Substitutes for plaquenil What can substitute for plaquenil? Yahoo Answers, Is there an alternative to Plaquenil? - Sjogren's World Taking plaquenil and hands still swollenChloroquine dose for prophylaxis The optimal treatment of RA requires a comprehensive program that combines medical, social, and emotional support for the patient. It is essential that the patient and the patient’s family be educated about the nature and course of the disease. Treatment options include medications, reduction of joint stress. Rheumatoid Arthritis Treatment Options Johns Hopkins.. Plaquenil Oral Uses, Side Effects, Interactions, Pictures.. Discontinued Plaquenil.other options?. Is there a drug that I can. Is there a drug that I can take to replace plaquenil? Asked by tanner01 Updated 5 April 2018 Topics plaquenil, rheumatoid arthritis, methotrexate. I take methotrexate also but the plaquenil messed with my vision and I had to quit taking it. I been treated for ra for 19 yrs. COMMON BRAND NAMES Plaquenil. Uses. This medication is used to treat rheumatoid arthritis and lupus; and to treat or prevent malaria. How To Use. Take this medication with food to prevent stomach upset. Take this medication exactly as prescribed. Do not stop taking it without consulting your doctor. Plaquenil is the brand name for the prescription drug hydroxychloroquine. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others.